I had to quit Flagyl because my peripheral neuropathy in my feet was getting worse. I didn't get my numb feet from taking it but one of the side effects is that and my ankles were starting to go numb too. It was a good one as long as I could take it. I had to take 5 rounds of it to kill my c.diff a few years ago.
I switched for the expensive Xifaxan an love it. I alternate every 2 weeks between it and augmentin. I got c.diff from taking Cipro when I still had my colon so can never take it again.
It's good that we have alternatives. Back in my parents time it was penicillin or penicillin.