Reply to "Diffuse lower back pain"

Lauren Of Emerald CityMember

@roseviolet posted:
Lauren, the explanation is below. I was told never to use NSAIDS again. It seems that some with pouches can take them without ill effect. I was taking them for migraine relief. Since the pouchitis attack, I've been switched to sumatriptan. --Rose
NSAIDs cause a dual assault on the GI tract: the acidic molecules directly irritate the gastric mucosa, and inhibition of COX-1 and COX-2 reduces the levels of protective prostaglandins .
Nonsteroidal anti-inflammatory drug - Wikipedia
en.wikipedia.org/wiki/Nonsteroidal_anti-inflammatory_drug#:~:text=NSAIDs cause a dual assault on the GI,and COX-2 reduces the levels of protective prostaglandins.

Thanks dear

11/25/207:59 PM

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