You need to find a surgeon who is very skilled with pouch advancement and mucosectomy before giving up on the pouch. I second Jan's recommendation to see someone at Cleveland Clinic . I would recommend Dr Remzi there. I have had similar issues due to a stricture and ongoing inflammation in my cuff and he is the surgeon I would pick if I ever have to advance my pouch. I have had relief with ongoing Canasa suppositories when I have alternated these w anucort also. Best of luck. I know this can be very frustrating and incredibly painful.