If it's possible for you, I would seek a 2nd opinion. I'm not a doctor, but it seems like a quick decision to start Humira. I was on Remicade for 21/2 years after a terrible bout of what my docs decided is Crohn's. After 21 days in the hospital, a microperforation of my pouch, and a fistula, we thought it was worth a try. One of the missing pieces were granulomas. Everyone is different, but I would like more information from my doctor.