So I took the paxlovid again because I got covid for a second time this past week. I again got the same symptoms, really bad butt burn and more frequent runny stools. It's crazy, but I had forgotten about starting this thread back in May. I had even forgot about the possible side effects I experienced the first time. Now I am wondering if my jpouch never really got that much better after my initial post. I did end up giving up coffee in August which really seemed to reduce to the butt burn to almost nothing, but I feel like I am having more rectal bleeding in general. My GI gave me Anucort suppositories and did not seem that concerned, but I still need to give a stool sample. I think I am going to request another scope just to put my mind at ease. It has been about 19 months since my last one. Hopefully it is jut my fissure and hemorrhoids. So has anybody else had elevated Pouch symptoms since having Covid or trying Paxlovid? Or does anyone have issues with bleeding and burn from fissure and or hemmorroids? Another change in my lifestyle is I have become more sexually active and as a female, I am wondering if that can irritate my pouch? I am told I have a rectocele as well.