Reply to "Costco is now limiting loperamide purchase to one box."

Actually Lomotil is diphenoxylate (plus a bit of atropine to discourage overuse), not loperamide. As folks upthread are saying, loperamide is Imodium. If loperamide purchases are being broadly curtailed, that will be a nuisance for many of us. I don't think it will prevent folks from getting what they need, but it might prevent stocking up, and add some extra trips to the pharmacy. I don't think there's much reason for panic buying or excessive stockpiling, since there's no reason to expect true shortages.

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