Reply to "Costco is now limiting loperamide purchase to one box."

Slouchy, I did a bit of research and found this.  It seems like the FDA may also be involved in the regulatory part of it, whereas DEA is more the illegal drug enforcement side of it:

https://www.fda.gov/Drugs/DrugSafety/ucm504617.htm

From that it sounds like narcotics users are taking imodium to self treat withdrawal symptoms and are ending up with serious heart problems.  How many imodiums one must consume to get "high" is an interesting question, but I suspect many would be needed to do that trick, if in fact it can even be done.

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