Thanks Jan, I took a look at the website and it was very informative. I have seemed to have exhausted all my other options for many of the biologics, my only other option was Nsaids now that my colitis was removed I thought I could try them again. I had very bad reactions to humira, imuran, methotrexate. Prednisone worked well, but isn't a long term medication due to the side effects. Thanks for sharing your story, sorry to hear what you are going through and hope all goes well with you in the future.