feirs1,
I rotated 7-8 different core antibiotics for nearly 25 years with success, tried many others. You can't stay on any 1 for too long or it will stop working. Rotate every 2 weeks and you can go on as long as I did. Xifaxin, Keflex, Augmentin, Levacquin (same family as cipro)) Flagyl, Doxycycline are other options.
There was eventually (after 25 years) attritional increases in the inflammation while my symptoms remained under control. For this reason I went on Remicade in 2015 and been on it ever since and antibiotics are now history. All I take now is Remicade.
Have you tried Entyvio, Stelara, or Humira? There are myriad other biologics options. I was told Entyvio is next up if Remicade ever fails, but it hasn't.
Good luck.