It can be very hard to figure out side effects when you combine drugs. Effective treatments are very, very precious when dealing with chronic pouchitis, so figuring out exactly which drug is causing the problem(s) is worth the trouble. I don’t see ringing ears (tinnitus) as a listed side effect of Cipro or Flagyl. Did you have any of these symptoms before you started the Cipro/Flagyl?
If I were you I’d get started on the request for Xifaxan approval.