My cost is $60 for 60 pills (1 month supply). How many per day do you take? How long have you been on it? Cipro or Flagyl didn't help my son. He's been on Xifaxin for 4 days and feels better already. I'm cautiously optimistic. I do not know how long he will stay on it yet. I am hoping not it's not permanent. When you go off the antibiotics your pouchitis comes right back again?