My 17 year old son had his takedown 6/2016. Did great his first year, but now has a stubborn case of pouchitis. He tried Cipro for 1 week which did not help and then Cipro and Flagyl for one month which did not help. Going to GI today to ask about Rifaximin and possibly Cortifoam as the next step to try. Has anyone had no luck with Cipro or Flagyl but then found that Rifaximin did the trick?