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Reply to "chronic pouchitis-Antibiotics (Levaquin)-Poucher from Shanghai"

CTBarrister posted:

Johnnycomelately,

Is the topical hydrogen peroxide administered by enema?

Jiajun,

Cipro and levacquin are indeed antibiotic cousins both in the fluoroquilones family of antibiotics. I was told never rotate from one onto the other. They are too close. Try tinidazole, or augmentin, or xifaxin. I have rotated antibiotics since 1995 for chronic Pouch inflammation. In 2015, I added Remicade which enabled me to decrease antibiotics dosages. If the antibiotics isn’t giving you complete relief, you probably do need to go to a biological drug.

 

The GI who I visted last time suggested me to swith to Cipro and xifaxan rotation. And also let me on oral mesalazine as well.  The combination of Xifaxian and oral mesalazine works well on me. My sympton got improved a lot. After 3 weeks on Xifaxian I switched to the combination of Cirpro and oral mesalazine, it still works, but not doing as good as Xifaxian doing. Since metronidazole not working and Levaquin makes me insomnia and depression. I want to know how long will it develops to Xifaxian resistance if all the other antibiotics does not respond to me except Xifaxian.  Due to the pubilc healthcare system in China is totall different from US, our insurance does not cover the expenses for biological agent in China. Very expensive. It cost around 15,000USD per year. Will be a big economic burden for the normal Chinese working class. So the biological agent will not be in my priority consideration except I have to be on it.  Strange that many of you Amercians complaint here that your insurance does not cover Xifaxian and expensive.  Unexpectedly, the pubilc health insurance in Shanghai covers Xifanxian.  It is affordable. 

BTW, thanks to Cleveland clinic's Dr Shen Bo, since he is a Chinese, most of the top surgeries ( mainly based in tier 1 Cities in China) in the fied has closely academic comunication and exchange with him.  The technique level is almost synchronous. 

 

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