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chronic pouchitis-Antibiotics (Levaquin)-Poucher from Shanghai

Hi,

I'm a j-poucher from Shanghai. Currently, IBD is dramatically rising in China due to rapidly industrialization. But the rate of J-pouch surgery is very low in China. Lack of related information. So I have to come to here for advice. I was originally diagnosed with UC 2008.  Later became steroid-dependent UC, intoleranted to azathioprine. had 2 step surgeries,  Colon removal and J-pouch creation- July, 2016. Take down-Dec 2016. My first pouchitits flare up was in 1 and half month after take down. And I was hospitalized for ten days then.  IV metronidazole, oral Levaquin and oral mesalazine put me in remission. Afterward I was on and off oral metronidazole and oral mesalazine for more than one year. I could eat whatever I want to have during the time.  3-6BM / 24H And most of the time my stool was firm and semi-firm. I was satisfied with my quality of my life in the time. But since late march this year, the pouchitis comes up again. 7-10BM/24 and stool became liquid or semi-liquid. Solo oral metronidazole does not works on me anymore. tries cipro and Xifaxan But none of them work on me either. Currently, I am put on oral metronidazole oral Levaquin and mesalazine suppository by GI. Seems help. Reduce to 6BM/24H. But my stool is still semi-liquid.  And had pouch-endoscope July 18. GI said the inflammation relieved compare with the scope which I had on May but the infammation and ulcers remains looks like chronic. Should take long time to clean up and cure. GI suggest me to keep on mesalazine and Levaquin. 

Is there any one here take Levaquin for long term?  Do you guys know what serious side effect consequence would be if to do so?  Currently. my sole of the foot feel slightly numbness. I'm not sure if it is coursed by Levaquin. 

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