Have you been trialed on any biologics like Remicade or Entyvio or Stelara? You sound like a prime candidate for that next step in treatment. When I got my Remicade infusion yesterday there was another woman in the infusion room with me and she said she had been on Remicade 10 years and hasn't had a single symptom since starting the treatment. She looked like she was in her 60s.