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Reply to "Celiac disease question ?"

Here are the ones my GI performed on me, these are my results, too.  So there were 5 tests in the panel. This was copy and pasted from the "Celiac Panel."  My tests were + for (1) and (5).

(1)  Evaluation of Transglutaminase Ab (IgA)
titer results:

Negative: Less than 20
Weak positive: 20 to 30
Positive: Greater than 30

Transglutaminase Ab is present in
approximately 95% to 100% of patients
with celiac disease and 80% of patients
with dermatitis herpetiformis.The
antibody is rarely found in other
conditions. Transglutaminase Ab levels
will decrease or increase depending on
the removal or reintroduction of gluten
into the diet. Patients who are IgA
deficient develop celiac disease more
frequently than individuals who have an
intact IgA system. Therefore, gliadin
and transglutaminase IgA antibodies may
be absent in patients with celiac
disease. IgG antibodies to gliadin are
especially helpful in IgA deficient
patients.
Gliadin Ab IgA <20 AU

MY Result:  30 H


(2)  Evaluation of Gliadin Abs (IgG,IgA)
results:

Negative: Less than 20
Weak positive: 20 to 30
Positive: Greater than 30

Both IgG and IgA antibodies to gliadin
are present in most patients with celiac
disease (CD). However, the antibodies
are not specific for CD. Antibody to
gliadin may be present in Crohn's
disease, dermatitis herpetiformis or in
subjects with no clinical evidence of
intestinal disease. In healthy
individuals with a family history of CD
the antibodies may precede the clinical
onset of disease in approximately 25% of
the subjects.
Gliadin antibody levels will decrease or
increase depending on the removal or
reintroduction of gluten into the diet.
Patients who are IgA deficient develop
celiac disease more frequently than
individuals who have an intact IgA
system. Therefore, gliadin and
transglutaminase IgA antibodies may be
absent in patients with celiac disease.
IgG antibodies to gliadin are especially
helpful in IgA deficient patients.
Gliadin Ab IgG <20

MY result:  AU 2


(3) IGG, SERUM 751-1560 mg/dL 1230

(4)  IGA 82-453 mg/dL 377


(5)  IGM 40-274 mg/dL 276 H
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