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Reply to "Biopsy’s"

It’s actually most important that the rectal cuff be biopsied. It’s the only colonic tissue remaining in your body. If you have any history of inflammation in the cuff or the pouch or a pre-surgical history of dysplasia, it absolutely should be biopsied every year. Cancer, although rare in J Pouchers, would be more likely to start in the rectal cuff than the Pouch with such histories.  My recollection is that Cleveland Clinic did a study on Pouch cancers about 9 years ago and my then GI, who interned with Dr. Shen there and was involved in the study, shared with me the results.  Pretty much all the cancers were in people who had severe uncontrolled pouchitis and/or cuffitis and it was originating in the rectal cuff.

Last edited by CTBarrister
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