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Biologics

If the colon is removed for the j pouch surgery, what good are biologics?  I’m in the midst of deciding whether to have my pouch removed or not due to constant pouchitis/cuffitis.  My gi has recommended biologics from time to time but I have declined. I tried entyvio, humira, and Remicade before j pouch surgery.  I’m just trying to get as much information as I can before making another surgical decision.  I just want to feel healthy again.  

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