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Reply to "Biologics"

Ulcers in the pouch tend to be a sign of significant pouchitis. There is a murky relationship between pouchitis and ulcerative colitis, but they definitely aren’t the same thing. Ulcers on the rectal cuff, though, seem to be the same as UC, but that’s called cuffitis rather than pouchitis. If your symptoms are responding to Cipro then there’s a good chance the ulcers will respond, too. That’s how it went for me. In most cases if the treatment is adequate the antibiotic can be stopped.

Unremitting pouchitis can be a cause of pouch failure, and pouchitis is sometimes treated with biologics, but both of those are “what if” scenarios. Right now you seem to be on the right treatment, and it seems to be working.

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