I was taking remicade 20 years ago. Or close to there.
It worked perfectly For several years. I felt normal. Until I was taken off of it for hernia surgery. No biologic ever worked after that. Not even remicade. That started me on a long painful journey.
But my first infusion made a difference. I could tell. And I said so but none of the people believed me. I was so sick when I started it. At he end of my two plus hour infusion I felt something. It was a good something and soon after that I had the best bowel movement I have had in a decade. I was right. I hate that I was taken off of it for surgery. Because while being treated for being sick again well after the hernia surgery one surgeon said I didn't have to be taken off it to have the surgery. Now. I have no colon. But also no hard feelings to what had happened. But I will vouch for remicade. I tried Humira afterwards and one other biologic. But neither worked again like the remicade. Which never worked again either.
Ahh. Such is life. Good luck. Hope you find something.
I do know from the remicade experience that if you don't get results after a few infusions it's not working. My opinion. Mine only. Never had one side effect from any biologic.
Richard.