I slept great coming home from the hospital. I was able to sleep through the night without taking anything until chronic pouchitis crept up on my about 6 weeks after takedown. I was told to not take any Imodium after takedown for several weeks. Don't take anything just because you think you might need it. Let your system regulate for a few weeks and then start to modify and throw in the bowel slowers and fiber and stuff. Keep hydrated as best you can. If you get up in the middle of the night to use the bathroom, make sure to get a drink as well.