My pouch is only 14, but I've been on budesonide for about 5 years and so far I haven't had any side effects from taking it this long. My pouch was misbehaving majorly when I began taking taking it. I couldn't sleep a full night without having to empty my pouch. My GI prescribed budesonide along with Imran and Amitriptylin to help me. I'm also on Entyvio, but that didn't start until a couple of years ago. I am so thankful that this combination has helped me sooo much! I sleep much better without my pouch keeping me up all night.
Each of the medicines I'm on carry warning labels and to be honest I am concerned about the long term affects. However, I realize my life is so much better with the meds, that it was without them. I actually feel like I have a life.
Congratulations on being a 30 plus year j poucher! May the Lord bless you with many more wonderful, health filled years.