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Allergic reaction to Apriso

MM Mama MiaMember
Hello everyone! I am new to the site. I have had my pouch for 25 years. I never had a problem until this past year. I had a scope done and my surgeon told me I had crohns. My GI prescribed Apriso. I am allergic to Sulfa so I was happy they now have sulfa free treatment. I had a terrible reaction to it. My chest hurt and then I had a stiff neck and low grade fever. He suggested I try pentasa but im afraid I might have the same reaction. Has anyone had a hard time tolerating Apriso and could tolerate Pentasa or Lialda?
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Jan DollarJan DollarModerator, RN, retired

Pentasa has the same active ingredient as Apriso, mesalamine. While allergy or acute intolerance are not common, they happen. Pentasa is not as delayed release as Apriso, so there may be more systemic absorption, which I think would increase your risk of a reaction. How about forgetting about mesalamine altogether and try something different like Imuran, methotrexate, or antibiotics? Mesalamine is no longer considered very effective for Crohn's. You can also try biologics if the other oral meds fail.

http://www.mayoclinic.org/dise...eatment/con-20032061

 

Jan

Last edited by Jan Dollar

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