I totally agree with ICROSSCO_1. It is exactly what I ended up doing, taking less meds. Today when the pouch gets crazy, I don't even take the med combo, I take two Aleve, takes away the inflammation and start to feel good again. I have had to take the med combo if I let things go too long without taking anything thinking "it will go away". I am learning to nip it in the bud, but, again, everyone is different, but definitely worth a try. Note: I do not take a lot of Aleve either. 2 pills one/day. I usually will take it before I go to sleep, takes away pain and I can usually sleep until early morning, feeling better when I get up and thru the day. If intolerant pain comes back, another 2 before bed, but really, one dose usually does it for me.
Being a 26 year Poucher, believe me, some of the side affects I have had to deal with because of meds is worse than the pouchitis.
My Story: 19-26 yrs old UC, 1991/26 Colon Removal/J Pouch/Take Down, Pouchitis from Crohns, 2002 fistulas, 2010 lots of fistulas, Could Be Worse cause I've been there - but life is still precious. Go to the mountains and get revived - amazing peace.